Cummins ISX Turbos - Top Models & Numbers

BigParts Part Number: 40-39318
Engine: Cummins ISX - various models 
Model Number: HE451VE
OEM Cross Reference Numbers: 3798515, 3781362, 3781369, 3795159, 3796346, 3796351, 3796391, 379639100, 379639100H, 379639100HX, 3796391H, 3796391HX, 3798515, 3798515NX, 3798515RX, 3798519, 379851900, 379851900H, 379851900HX, 3798519H, 3798519HX, 4309273, 4309273NX, 4309273RX, 5354718, 5354719, 5354719H, 5354721, 5354721H, 5354721HX, 5458260, 5458260NX, 5458260RX 

BigParts Part Number: 40-39320
Engine: Cummins ISX , ISX15 and QSX high HP 
Model Number: HE451VE
OEM Cross Reference Numbers: 2843821, 2882015, 2882015NX, 2882015RX, 2882112, 288211200, 288211200HX, 288211200NX, 288211200RX, 2882112H, 2882112NX, 2882112RX, 3769054, 3769055, 3769056, 3769058, 3769059, 3769061, 3773488, 3773489, 3773491, 3773492, 3773493, 3773495, 3792570, 3792571, 3792576, 379257600, 379257600H, 3792576H, 3792577, 3792583, 379258300, 379258300H, 3792583H, 3795122, 3795142, 3795143, 5350404, 5350411, 5350411RX, 5350499, 5350501, 535050100, 5350501H, 5359590, 5359595, 5359603, 5359609, 5359609NX, 5359609RX, 5456845, 5456845H, 5458503, 5458503NX, 5458503RX 

BigParts Part Number: 40-39319
Engine: Cummins ISX, ISX15 - 24V models 
Model Number: HE451VE
OEM Cross Reference Numbers: 3777139, 3777141, 3781360, 3781367, 3795157, 3796349, 3796389, 3798514, 3798514NX, 3798514RX, 3798518, 4309271, 4309271NX, 4309271RX, 5350588, 5350953, 535095300, 535095300H, 5350953H, 5354714, 5354715, 5354716, 535471600, 535471600H, 535471600HX, 5354716H, 5354716HX, 5354717, 535471700, 535471700H, 535471700HX, 5354717H, 5354717HX, 5354723, 5354725, 5354725H, 5354725HX, 5357368, 5357368NX, 5357368RX, 5359598, 5458272, 5458272RX

BigParts Part Number: 40-39132
Engine: Cummins ISX , ISX15 low HP 
Model Number: HE451VE
OEM Cross Reference Numbers: 2840007, 2840007, 2840007, 2841220, 2841220, 2841220, 2841221, 2841221, 2841221, 2841806, 2841806, 2841806, 2881807, 2881807, 2881807, 2881807NX, 2881807NX, 2881807NX, 2881807RX, 2881807RX, 2881807RX, 2882004, 2882004, 2882004, 2882004NX, 2882004NX, 2882004NX, 2882004RX, 2882004RX, 2882004RX, 2882111, 2882111, 2882111, 288211100, 288211100, 288211100, 288211100H, 288211100HX, 288211100HX, 288211100HX, 288211100NX, 288211100NX, 288211100NX, 288211100RX, 288211100RX, 288211100RX, 2882111H, 2882111H, 2882111H, 2882111HX, 2882111NX, 2882111NX, 2882111NX, 2882111RX, 2882111RX, 2882111RX, 3767305, 3767305, 3767305, 3767306, 3767306, 3767306, 3768193, 3768193, 3768193, 3768193NX, 3768193NX, 3768193NX, 3768193RX, 3768193RX, 3768193RX, 3768194, 3768194, 3768194, 3773561, 3773561, 3773561, 3773562, 3773562, 3773562, 3773568, 3773568, 3773568, 3773568NX, 3773568NX, 3773568NX, 3773568RX, 3773568RX, 3773568RX, 3773569, 3773569, 3773569, 3792574, 3792574, 3792574, 3792581, 3792581, 3792581, 3792586, 3792586, 3792586, 379258600H, 379258600H, 379258600H, 379258600HX, 379258600HX, 379258600HX, 3792586H, 3792586H, 3792586H, 3792586HX, 3792586HX, 3792586HX, 3795123, 3795123, 3795123, 3795123NX, 3795123NX, 3795123NX, 3795123RX, 3795123RX, 3795123RX, 3795144, 3795144, 3795144, 4627462, 5350503, 5350503, 5350503, 5350506, 5350506, 5350506, 5454764, 5454764, 5454764, 5454764NX, 5454764NX, 5454764NX, 5454764RX, 5454764RX, 5454764RX, 5501254, 5501254, 5501254, 550125400H, 550125400H, 550125400H, 5501254H, 5501254H, 5501254H, 5501254HX, 5501254HX, 5501254HX, 5501313, 5501313, 5501313, 5501313NX, 5501313NX, 5501313NX, 5501313RX, 5501313RX, 5501313RX, 5502825, 5502825, 5502825, 5502825NX, 5502825NX, 5502825NX, 5502825RX, 5502825RX, 5502825RX

BigParts Part Number: 40-31542
Engine: Cummins ISX15, 2010 and prior
Model Number: HE561VE
OEM Cross Reference Numbers: 2836364, 2836365, 2838149, 2838150, 2840531, 2840532, 2881789, 2881789NX, 2881789RX, 2882000, 2882000NX, 2882000RX, 3767612, 3767618, 3767625, 3767633, 3774604, 3774614, 3774628, 3774642, 3792775, 3792785, 3792795, 379279500, 379279500H, 379279500HX, 3792795H, 3792795HX, 3795165, 4048097, 4048098, 4309078, 4309078NX, 4309078RX, 4955801, 4955801NX, 4955801RX, 4956014, 4956014NX, 4956014RX, 5350518, 5350591, 5350951, 5355397, 5355403, 5495611, 5495611H, 5495611HX, 5495621, 5495621NX, 5495621RX

BigParts Part Number: 40-39410
Engine: Cummins X152018+, low HP
Model Number: HE400VG
OEM Cross Reference Numbers: 5351486, 5351487, 5351487NX, 5351487RX, 5351489, 5351490, 5351491, 5358001, 5358001NX, 5358001RX, 5358452, 5358452NX, 5358452RX, 5358453, 5358453NX, 5358453RX, 5358454, 5454976, 5454977, 5454978, 5458936, 545893600, 545893600H, 5458936H, 5458936HX, 3768264, 3768264NX, 3768264RX

BigParts Part Number: 40-39409
Engine: Cummins X15 2018+, high HP
Model Number: HE400VG
OEM Cross Reference Numbers: 5327132, 5350586, 5351565, 5351565NX, 5351565RX, 5351566, 5351566NX, 5351566RX, 5358003, 5358003RX, 5358483, 5358483RX, 5358484, 5358485, 5454982, 5454982RX, 5454983, 5454984, 5458937, 545893700, 545893700H, 5458937H, 5458937HX, 5459711, 5459711NX, 5459711RX

BigParts Part Number: 40-30383
Engine: Cummins Early ISX, non-electronic 
Model Number: HE551V
OEM Cross Reference Numbers: 2842412, 2843888, 2843889, 2881994, 288199400, 288199400HX, 2881994NX, 2881994RX, 3597982, 3598821, 3598822, 3598824, 3598826, 3599626, 3599627, 3768264, 3768268, 376826800HX, 3768268H, 3768268HX, 3768269, 4035603, 4035604, 4035677, 4035678, 4036666, 4041090, 4043215, 4043226, 4045753, 4089152, 4089152NX, 4089152RX, 4089398, 4089398NX, 4089398RX, 4089551, 4089551NX, 4089551RX, 4955306, 4955306NX, 4955306RX, 5352715

BigParts Part Number: 40-30522
Engine: Cummins Signature ISX04, Signature ISX QSX15
Model Number: HE500VG
OEM Cross Reference Numbers: 2842411, 2843886, 2843887, 2881993, 288199300, 288199300HX, 2881993NX, 2881993RX, 3768263, 3768267, 376826700HX, 3768267H, 3768267HX, 4036719, 4036720, 4041076, 4043214, 4043225, 4045752, 4089713, 4089713NX, 4089713RX, 4955305, 4955305NX, 4955305RX, 5352714

BigParts Part Number: 40-31335
Engine: Cummins ISX15  15L  07-13 Volvo
Model Number: HE561VE
OEM Cross Reference Numbers: 2836356, 2836357, 2838153, 2838154, 2840519, 2840520, 2840521, 2881785, 2881785NX, 2881785RX, 2881997, 2881997NX, 2881997RX, 3767615, 3767622, 3767630, 3774601, 3774612, 3774626, 3774640, 3780526, 3792776, 3792786, 3795162, 4042413, 4045031, 4045034, 4309076, 430907600, 430907600HX, 4309076HX, 4309076NX, 4309076RX, 4620744, 4955425, 4955425NX, 4955425RX, 4956010, 4956010NX, 4956010RX, 5350611, 5350641, 535064100, 5350641H, 5350893, 535089300H, 5350893H, 5350893HX, 5355196, 535519600, 535519600HX, 5355196H, 5355196HX, 5359785, 5359785NX, 5359785RX, 5359785RX]75, 5359785RX75, 5456738, 545673800H, 5456738H, 5456738HX, 5456815, 545681500, 545681500H, 545681500HX, 5456815H, 5456815HX, 5457297, 5457297NX, 5457297RX

BigParts Part Number: 40-39312
Engine: Cummins Various   ISX-EGR, ISX15 Volvo
Model Number: HE500VG
OEM Cross Reference Numbers: 2836358, 2836359, 2838008, 2838009, 2840523, 2840524, 2840525, 2843356, 2843359, 2881786, 2881786NX, 2881786RX, 2881988RX, 2881998, 2881998NX, 2881998RX, 3767616, 3767623, 3767631, 3769880, 3769882, 3774602, 3774613, 3774627, 3774641, 3776665, 3776666, 3776669, 4042417, 4045032, 4045035, 4048260, 4048261, 4309077, 430907700, 430907700HX, 4309077HX, 4309077NX, 4309077RX, 4955426, 4955903, 4956011, 4956011NX, 5350895, 5350895H, 5350895HX, 5456817, 5456817H, 5456817HX, 5457298, 5457298NX, 5457298RX

Cummins ISX Engine Overview

The Cummins ISX is one of the most recognized heavy-duty diesel engines in the trucking and industrial world. Designed for Class 8 trucks and other demanding applications, the ISX has earned a reputation for power, durability, and advanced engineering. Whether you’re running long-haul freight, heavy construction, or vocational operations, the ISX remains a proven performer.

Key Features of the Cummins ISX Engine

- Displacement: 14.9 liters (commonly referred to as a 15L engine)
- Horsepower Range: 400 – 600+ HP depending on the model and application
- Torque Output: Up to 2,050 lb-ft of torque for heavy hauling capability
- Fuel System: High-pressure fuel injection for improved efficiency
- Variable Geometry Turbocharger (VGT): Optimized airflow for performance across RPM ranges
- Aftertreatment Systems: Incorporates EGR (Exhaust Gas Recirculation), DPF (Diesel Particulate Filter), and SCR (Selective Catalytic Reduction) to meet EPA emissions standards

Variants and Evolution

The ISX engine has gone through several versions since its introduction in the early 2000s:

- ISX CM570: Early model known for mechanical simplicity.
- ISX CM870 / CM871: Introduced emissions controls with EGR and later DPF systems.
- ISX15 CM2250 / CM2350: Featured SCR aftertreatment for stricter EPA standards.
- X15 Series (2017+): Successor to the ISX15, offering three configurations — Efficiency, Performance, and Productivity.

Applications of the Cummins ISX

The ISX is widely used in:
- Over-the-Road Trucks: Freightliner, Peterbilt, Kenworth, International, Volvo, and Western Star models.
- Vocational Trucks: Dump trucks, mixers, logging trucks, and other heavy-duty vocational vehicles.
- Industrial Equipment: Some models adapted for mining, oilfield, and construction operations.

Advantages of the Cummins ISX

- High Durability: Built for long-haul applications with extended service intervals.
- Strong Torque Curve: Provides excellent pulling power for steep grades and heavy loads.
- Advanced Electronics: On-board diagnostics and electronic control modules for improved maintenance monitoring.
- Fuel Efficiency: Competitive fuel economy compared to other heavy-duty diesels.
- Parts Availability: Widely supported with OEM and aftermarket replacement parts.

Common Maintenance & Service Considerations

Like any advanced diesel, the ISX has its maintenance needs:
- EGR & DPF Cleaning: Required at intervals to maintain emissions compliance.
- Fuel System Care: Clean, high-pressure fuel injection requires quality filters.
- Turbocharger Maintenance: VGT turbos must be inspected for soot buildup.
- Overhead Adjustment: Periodic valve and injector adjustments ensure proper engine timing.

Why the Cummins ISX Stands Out

The Cummins ISX has become a benchmark for heavy-duty diesel performance. Its combination of raw power, technological sophistication, and aftermarket support has made it a preferred engine for fleet managers and independent truckers alike.

Need replacement parts for your Cummins ISX? From turbochargers and injectors to complete overhaul kits, we’ve got you covered.